Streptolysin

Streptolysin is a streptococcal hemolytic exotoxin.^[1]^[2]

Types include streptolysin O (SLO), which is oxygen-labile, and streptolysin S (SLS), which is oxygen-stable.^[3]

An antibody, antistreptolysin O, can be detected in an antistreptolysin O titre.

Streptolysin O is hemolytically active only in a reversibly reduced state, unlike streptolysin S, which is stable in the presence of oxygen. Another difference is that that SLO is antigenic, while SLS is not antigenic due to its small size.

References

^ "streptolysin" at Dorland's Medical Dictionary
^ Streptolysin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
^ Sierig G, Cywes C, Wessels MR, Ashbaugh CD (January 2003). "Cytotoxic effects of streptolysin o and streptolysin s enhance the virulence of poorly encapsulated group a streptococci". Infect. Immun. 71 (1): 446–55. doi:10.1128/IAI.71.1.446-455.2003. PMC 143243. PMID 12496195.{{cite journal}}: CS1 maint: multiple names: authors list (link)

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[1] "streptolysin" at Dorland's Medical Dictionary

[2] Streptolysin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

[pmid12496195-3] Sierig G, Cywes C, Wessels MR, Ashbaugh CD (January 2003). "Cytotoxic effects of streptolysin o and streptolysin s enhance the virulence of poorly encapsulated group a streptococci". Infect. Immun. 71 (1): 446–55. doi:10.1128/IAI.71.1.446-455.2003. PMC 143243. PMID 12496195.{{cite journal}}: CS1 maint: multiple names: authors list (link)

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v t e Protein: cell membrane proteins (other than Cell surface receptor, enzymes, and cytoskeleton)
Arrestin	SAG ARRB1 ARRB2 ARR3
Membrane-spanning 4A	MS4A1 MS4A2 MS4A3 MS4A4A MS4A4E MS4A5 MS4A6A MS4A6E MS4A7 MS4A8B MS4A9 MS4A10 MS4A12 MS4A13 MS4A14 MS4A15 MS4A18
Myelin	Myelin basic protein PMP2 Myelin proteolipid protein PLP1 Myelin oligodendrocyte glycoprotein Myelin-associated glycoprotein Myelin protein zero
Pulmonary surfactant	Pulmonary surfactant-associated protein B Pulmonary surfactant-associated protein C
Tetraspanin	TSPAN1 TSPAN2 TSPAN3 TSPAN4 TSPAN5 TSPAN6 TSPAN7 TSPAN8 TSPAN9 TSPAN10 TSPAN11 TSPAN12 TSPAN13 TSPAN14 TSPAN15 TSPAN16 TSPAN17 TSPAN18 TSPAN19 TSPAN20 TSPAN21 TSPAN22 TSPAN23 TSPAN24 TSPAN25 TSPAN26 TSPAN27 TSPAN28 TSPAN29 TSPAN30 TSPAN31 TSPAN32 TSPAN33 TSPAN34
Other/ungrouped	Calnexin LDL-receptor-related protein-associated protein Neurofibromin 2 Presenilin PSEN1 PSEN2 HFE Phospholipid transfer proteins Dysferlin STRC OTOF
see also other cell membrane protein disorders