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Hypodermoclysis, which can also be called interstitial infusion or subcutaneous infusion, is the subcutaneous administration of fluids to the body. This would often be in the form of a saline or glucose solution.[1]

Hypodermoclysis can be used where a slow rate of fluid uptake is required compared to intravenous infusion. Typically, it is limited to 1 ml per minute, although it is possible to increase this by using two sites simultaneously. The chief advantages of hypodermoclysis over intravenous infusion is that it is cheap and can be administered by non-medical personnel with minimal supervision. It is therefore particularly suitable for home care.[2]

Hyaluronidase can improve absorption via hypodermoclysis.

See also[edit]


  1. ^ "hypodermoclysis", Merriam-Webster's medical dictionary online.
  2. ^ Menahem Sasson, Pesach Shvartzman, "Hypodermoclysis: An Alternative Infusion Technique", American Family Physician, Vol. 64, No. 9 (November 1, 2001).