Succinyl-CoA hydrolase

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succinyl-CoA hydrolase
Identifiers
EC number3.1.2.3
CAS number9025-86-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

In enzymology, a succinyl-CoA hydrolase (EC 3.1.2.3) is an enzyme that catalyzes the chemical reaction

succinyl-CoA + H2O CoA + succinate

Thus, the two substrates of this enzyme are succinyl-CoA and H2O, whereas its two products are CoA and succinate.

This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name of this enzyme class is succinyl-CoA hydrolase. Other names in common use include succinyl-CoA acylase, succinyl coenzyme A hydrolase, and succinyl coenzyme A deacylase. This enzyme participates in citrate cycle (tca cycle).

References[edit]

  • Gergely J, Hele P, Ramakrishnan CV (1952). "Succinyl and acetyl coenzyme A deacylases". J. Biol. Chem. 198 (1): 323–334. PMID 12999747.