Succinyldiaminopimelate transaminase

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succinyldiaminopimelate transaminase
Identifiers
EC number 2.6.1.17
CAS number 9030-46-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a succinyldiaminopimelate transaminase (EC 2.6.1.17) is an enzyme that catalyzes the chemical reaction

N-succinyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate N-succinyl-L-2-amino-6-oxoheptanedioate + L-glutamate

Thus, the two substrates of this enzyme are N-succinyl-L-2,6-diaminoheptanedioate and 2-oxoglutarate, whereas its two products are N-succinyl-L-2-amino-6-oxoheptanedioate and L-glutamate.

This enzyme belongs to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is N-succinyl-L-2,6-diaminoheptanedioate:2-oxoglutarate aminotransferase. Other names in common use include succinyldiaminopimelate aminotransferase, and N-succinyl-L-diaminopimelic glutamic transaminase. This enzyme participates in lysine biosynthesis. It employs one cofactor, pyridoxal phosphate.

References[edit]

  • Peterkofsky B; Gilvarg C (1961). "N-Succinyl-L-diaminopimelic-glutamic transaminase". J. Biol. Chem. 236: 1432–1438. PMID 13734750.