Suloctidil

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Suloctidil
Suloctidil.png
Clinical data
ATC code
Identifiers
CAS Number
PubChem CID
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.053.920 Edit this at Wikidata
Chemical and physical data
FormulaC20H35NOS
Molar mass337.563 g·mol−1
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Suloctidil was a sulfur-containing aminoalcohol that was brought to market in the early 1970s as a vasodilator by Continental Pharma, a Belgian company.[1]:118–121[2]

Continental was bought by Monsanto in 1984, primarily on the promise of sales of suloctidil, which was approved in Europe at the time, but not in the US.[3] However, in 1985 Monsanto halted development and withdrew the drug worldwide following reports of liver toxicity.[4]:251

References[edit]

  1. ^ Josef Hladovec. Antithrombotic Drugs in Thrombosis Models. CRC Press, 1989 ISBN 9780849351624
  2. ^ Roncucci R et al. Potential antilipolytic activity of suloctidil. Naturwissenschaften. 1975 Mar;62(3):141-2 PMID 1240601. Paper cites Belgian patent 739678
  3. ^ Staff, The Pink Sheet. November 5 1984 Monsanto's $150 mil. Life Sciences Research Center
  4. ^ Department of Economic and Social Affairs of the United Nations Secretariat Consolidated List of Products Whose Consumption and/or Sale Have Been Banned, Withdrawn, Severely Restricted or not Approved by Governments Twelfth Issue: Pharmaceuticals United Nations – New York, 2005