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Combination of
Sulfacetamide Sulfonamide antibacterial
Sulfur (pharmacy) Keratolytic
Clinical data
AHFS/ Multum Consumer Information
License data
  • US: C (Risk not ruled out)
Routes of
Legal status
Legal status

The drug combination sulfacetamide/sulfur is a topical acne medication manufactured by Medicis under the trade name Plexion and also available under other trade names such as Clenia, Prascion, and Avar. It combines sodium sulfacetamide, a sulfonamide antibiotic, and sulfur, a keratolytic agent.[1] It is available in four formulations: as a cleansing cloth, cleanser, topical suspension, and as a facial mask. The sulfacetamide inhibits the growth of the bacterium Propionibacterium acnes that is associated with acne, while sulfur facilitates the removal of dead skin cells to prevent clogged pores.[2]


  1. ^ "PLEXION (R) (sodium sulfacetamide 10% and sulfur 5%)". Medicis Inc. Retrieved 2008-12-02. 
  2. ^ "PLEXION Prescribing information" (PDF). Medicis. Retrieved 2008-12-02.