Sulfadimethoxine

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Sulfadimethoxine
Sulfadimethoxine.svg
Sulfadimethoxine ball-and-stick model.png
Clinical data
AHFS/Drugs.com FDA Professional Drug Information
ATC code
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
ECHA InfoCard 100.004.113
Chemical and physical data
Formula C12H14N4O4S
Molar mass 310.33 g/mol
3D model (Jmol)
  (verify)

Sulfadimethoxine (trade name Di-Methox, Albon) is a sulfonamide antimicrobial medication used in veterinary medicine. It is used to treat many infections including treatment of respiratory, urinary tract, enteric, and soft tissue infections.[5] Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic acid) from para-aminobenzoic acid. It is also commonly used for the treatment of coccidiosis in many species.[1] Albon is produced by Pfizer Animal Health and is available as an oral suspension, tablet or bolus.

Sulfadimethoxine is approved in Russia for use in humans, including children, and has been successfully used there for more than 35 years.[2] It is widely available in Russia as an over-the-counter drug manufactured by a number of Russian pharmaceutical companies.

Side Effects[edit]

Some side effects include:

  • Redness of the eye[3]
  • Discharge from the eye
  • Other symptoms related to the eye
  • Bleeding
  • Vomiting and diarrhea
  • Increased thirst is common[4]
  • Incessant itch

Animals should be kept well hydrated to prevent the formation of sulfa crystals in the animal's urine.[6]

Uses[edit]

It can be used for:[5]

  • metritis
  • tonsillitis
  • pharyngitis
  • pneumonia
  • pyometra
  • anal gland infections
  • dermatitis
  • wounds and abscesses
  • enteritis
  • salmonellosis
  • enteritis associated with coccidiosis in dogs

Actions[edit]

It has been shown to be effective against streptococci, klebsiella, proteus, shigella, staphylococci, escherichia, and salmonella.

Notes[edit]

External links[edit]