Sulfafurazole

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Not to be confused with sulfadiazine.
Sulfafurazole
Sulfafurazole.svg
Systematic (IUPAC) name
4-amino-N-(3,4-dimethyl-1,2-oxazol-5-yl)benzenesulfonamide
Clinical data
AHFS/Drugs.com International Drug Names
MedlinePlus a601049
Pregnancy
category
  • To be avoided within two months of term
Routes of
administration
Oral
Legal status
Legal status
  • ℞ (Prescription only)
Pharmacokinetic data
Excretion Excreted unchanged in urine
Identifiers
CAS Number 127-69-5 YesY
ATC code J01EB05 (WHO) S01AB02 (WHO) QJ01EQ05 (WHO)
PubChem CID 5344
DrugBank DB00263 N
UNII 740T4C525W N
KEGG D00450 YesY
ChEMBL CHEMBL453 N
Chemical data
Formula C11H13N3O3S
Molar mass 267.30 g/mol
Physical data
Melting point 194 °C (381 °F)
 NYesY (what is this?)  (verify)

Sulfafurazole (INN, also known as sulfisoxazole) is a sulfonamide antibacterial with an oxazole substituent. It has antibiotic activity against a wide range of Gram-negative and Gram-positive organisms. It is sometimes given in combination with erythromycin (see erythromycin/Sulfafurazole) or phenazopyridine. It is used locally in a 4% solution or ointment.

Synthesis[edit]

Sulfisoxazole synthesis: U.S. Patent 2,430,094 GB 595775 

See also[edit]

External links[edit]