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Sulfathiazole skeletal.svg
Sulfathiazole substance photo.jpg
Systematic (IUPAC) name
Clinical data
AHFS/ International Drug Names
CAS Number 72-14-0 YesY
ATC code D06BA02 J01EB07 QJ01EQ07
PubChem CID: 5340
DrugBank DB06147 YesY
ChemSpider 5148 YesY
KEGG D01047 YesY
Chemical data
Formula C9H9N3O2S2
Molecular mass 255.319 g/mol
Physical data
Melting point 202 to 202.5 °C (395.6 to 396.5 °F)
 YesY (what is this?)  (verify)

Sulfathiazole is an organosulfur compound used as a short-acting sulfa drug. It is an organic compound. Formerly, it was a common oral and topical antimicrobial, until less toxic alternatives were discovered. It is still occasionally used, sometimes in combination with sulfabenzamide and sulfacetamide, and in aquariums.

It exists in various forms (polymorphs). The imine tautomer is dominant, at least in the solid state. In this tautomer, the proton resides on the ring nitrogen, not the structure shown above.[1]

Cultural references[edit]

Sulfathiazole is mentioned in chapter 104 of Kurt Vonnegut's novel Cat's Cradle and New Dictonary, and several of his short stories. Thomas Heggen's 1946 novel Mister Roberts mentions the use of sulfathiazole to treat gonorrhea, and Sonya Dorman's short story When I was Miss Dow in 1966. Also the 1988 movie Dead Heat mentions the chemical as a drug used with reanimation of dead bodies.

Sulfathiazole is mentioned in "The World According To Garp" in chapter 1 where Garps mother witnesses it being dispensed to WWII soldiers.


  1. ^ G. J. Kruger and G. Gafner "The crystal structure of sulphathiazole II" Acta Cryst. (1971). B27, 326-333.doi:10.1107/S0567740871002176