Sulfite dehydrogenase

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sulfite dehydrogenase
EC number
CAS number 37256-47-6
IntEnz IntEnz view
ExPASy NiceZyme view
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / QuickGO

In enzymology, a sulfite dehydrogenase (EC is an enzyme that catalyzes the chemical reaction

sulfite + 2 ferricytochrome c + H2O sulfate + 2 ferrocytochrome c + 2 H+

The 3 substrates of this enzyme are sulfite, ferricytochrome c, and H2O, whereas its 3 products are sulfate, ferrocytochrome c, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on a sulfur group of donor with a cytochrome as acceptor. The systematic name of this enzyme class is sulfite:ferricytochrome-c oxidoreductase. Other names in common use include sulfite cytochrome c reductase, sulfite-cytochrome c oxidoreductase, and sulfite oxidase. This enzyme participates in sulfur metabolism.


  • Charles AM; Suzuki I (1966). "Purification and properties of sulfite:cytochrome c oxidoreductase from Thiobacillus novellus". Biochim. Biophys. Acta. 128: 522–534. doi:10.1016/0926-6593(66)90013-0. 
  • Lu, W-P; Kelly DP (1984). "Properties and role of sulphite:cytochrome c oxidoreductase purified from Thiobacillus versutus (A2)". J. Gen. Microbiol. 130: 1683–1692. doi:10.1099/00221287-130-7-1683.