|3D model (Jmol)||Interactive image|
|Molar mass||177.29 g/mol|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|what is ?)(|
Sulforaphane is a compound within the isothiocyanate group of organosulfur compounds. It is obtained from cruciferous vegetables such as broccoli, Brussels sprouts or cabbages. It is produced when the enzyme myrosinase transforms glucoraphanin, a glucosinolate, into sulforaphane upon damage to the plant (such as from chewing), which allows the two compounds to mix and react. Young sprouts of broccoli and cauliflower are particularly rich in glucoraphanin.
glucoraphanin, glucosinolate precursor to sulforaphane
Occurrence and isolation
Sulforaphane was identified in broccoli sprouts, which, of the cruciferous vegetables, have the highest concentration of sulforaphane. It is also found in Brussels sprouts, cabbage, cauliflower, bok choy, kale, collards, Chinese broccoli, broccoli raab, kohlrabi, mustard, turnip, radish, arugula, and watercress.
Basic research on sulforaphane includes how it may affect neurodegenerative disorders, cancer, spinal cord injury or gastric diseases, and preliminary human research on autism. As of 2015[update], clinical trials are being conducted with sulforaphane for autism spectrum disorder.
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- Moon JK, Kim JR, Ahn YJ, Shibamoto T (2010). "Analysis and anti-Helicobacter activity of sulforaphane and related compounds present in broccoli ( Brassica oleracea L.) sprouts". J. Agric. Food Chem. 58 (11): 6672–7. doi:10.1021/jf1003573. PMID 20459098.
- Singh, Kanwaljit; Connors, Susan L.; Macklin, Eric A.; Smith, Kirby D.; Fahey, Jed W.; Talalay, Paul; Zimmerman, Andrew W. (28 October 2014). "Sulforaphane treatment of autism spectrum disorder (ASD)". Proceedings of the National Academy of Sciences. 111 (43): 15550–15555. doi:10.1073/pnas.1416940111. ISSN 0027-8424. PMC . PMID 25313065.
- "Sulforaphane Treatment of Children With Autism Spectrum Disorder (ASD)". clinicaltrials.gov. Retrieved 3 May 2016.