Superior longitudinal fasciculus
|Superior longitudinal fasciculus|
|Latin||fasciculus longitudinalis superior cerebri|
|Anatomical terms of neuroanatomy|
The superior longitudinal fasciculus (also called the superior longitudinal fascicle or SLF) is a pair of long bi-directional bundles of neuronal axons (white matter tracts) connecting the front and back of the cerebrum. Each association fiber bundle (one on each side) is lateral to the centrum ovale of a cerebral hemisphere and connects the frontal, occipital, parietal, and temporal lobes. These bundles of axon tracts pass from the frontal lobe through the operculum to the posterior end of the lateral sulcus where they either radiate to and synapse on neurons in the occipital lobe or turn downward and forward around the putamen and then radiate to and synapse on neurons in anterior portions of the temporal lobe.
The SLF is composed of four distinct components SLF I, SLF II, SLF III, and arcuate fascicle (AF). In humans, these four components are bundled together although they are functionally separate. In non-human primates, the SLF and AF are anatomically separate and have separate trajectories.
SLF I is the dorsal component and originates in the superior and medial parietal cortex, passes around the cingulate sulcus and in the superior parietal and frontal white matter, and terminates in the dorsal and medial cortex of the frontal lobe (Brodmann 6, 8, and 9) and in the supplementary motor cortex (M II).
SLF III is the ventral component and originates in the supramarginal gyrus (rostral portion of the inferior parietal lobe) and terminates in the ventral premotor and prefrontal cortex (Brodmann 6, 44, and 46).
The AF originates in the caudal area of the superior temporal gyrus and passes next to the neurons of SLF II above the Sylvian fissure and insula in non-human primates. In humans, neurons that originate from the caudal superior temporal gyrus and the superior temporal sulcus pass around the caudal Sylvian fissure and along with the SLF bundle and terminate in the dorsal prefrontal cortex (Brodmann areas 8 and 46).
SLF I connects to the superior parietal cortex which encodes locations of body parts in a body-centric coordinate system and with M II and dorsal premotor cortex. This suggests the SLF I is involved with regulating motor behavior, especially conditional associative tasks which select among competing motor tasks based on conditional rules.
SLF II connects to the caudal inferior parietal cortex which controls spatial attention and visual and oculomotor functions. This suggests the SLF II provides the prefrontal cortex with parietal cortex information regarding perception of visual space. Since these bundles are bi-directional, working memory (Brodmann 46) in the prefrontal cortex may provide the parietal cortex with information to focus spatial attention and regulate selection and retrieval of spatial information.
SLF III connects the rostral inferior parietal cortex which receives information from the ventral precentral gyrus. This suggests that the SLF III transfers somatosensory information, such as language articulation, between the ventral premotor cortex, Brodmann 44 (pars opercularis), the supramarginal gyrus (Brodmann 40), and the laterial inferior prefrontal cortex working memory (Brodmann 46).
- Makris pages 1-2
- Kamali, A; Flanders, AE; Brody, J; Hunter, JV; Hasan, KM (2014). "Tracing superior longitudinal fasciculus connectivity in the human brain using high resolution diffusion tensor tractography". Brain Struct Funct. 219: 269–81. doi:10.1007/s00429-012-0498-y. PMID 23288254.
- Makris page 11
- Makris page 13
- Makris page 14
|Wikimedia Commons has media related to Superior longitudinal fasciculus.|
- Makris N, et al. (2005). "Segmentation of subcomponents within the superior longitudinal fascicle in humans: a quantitative, in vivo, DT-MRI study". Cereb. Cortex. 15 (6): 854–69. doi:10.1093/cercor/bhh186. PMID 15590909.
- Brainmind.com atlas, see "1. Short arcuate bundles" section. Bundle 2 is the superior longitudinal fasciculus
- brain atlas sagittal images showing the SLF (bundle 2)
- Atlas image: n1a5p6 at the University of Michigan Health System - "Dissection of the Left Hemisphere"