Surface-assisted laser desorption/ionization
Surface-assisted laser desorption/ionization (SALDI) is a soft laser desorption technique used for analyzing biomolecules by mass spectrometry. In its first embodiment, it used graphite matrix. At present, laser desorption/ionization methods using other inorganic matrices, such as nanomaterials, are often regarded as SALDI variants. A related method named "ambient SALDI" - which is a combination of conventional SALDI with ambient mass spectrometry incorporating the DART ion source - has also been demonstrated.
- Sunner, Jan.; Dratz, Edward.; Chen, Yu-Chie. (1995). "Graphite surface-assisted laser desorption/ionization time-of-flight mass spectrometry of peptides and proteins from liquid solutions". Analytical Chemistry 67 (23): 4335–4342. doi:10.1021/ac00119a021. ISSN 0003-2700. PMID 8633776.
- Dattelbaum, Andrew M; Iyer, Srinivas (2006). "Surface-assisted laser desorption/ionization mass spectrometry". Expert Review of Proteomics 3 (1): 153–161. doi:10.1586/14789418.104.22.168. ISSN 1478-9450. PMID 16445359.
- Zhang, Jialing; Li, Ze; Zhang, Chengsen; Feng, Baosheng; Zhou, Zhigui; Bai, Yu; Liu, Huwei (2012). "Graphite-Coated Paper as Substrate for High Sensitivity Analysis in Ambient Surface-Assisted Laser Desorption/Ionization Mass Spectrometry". Analytical Chemistry 84 (7): 3296–3301. doi:10.1021/ac300002g. ISSN 0003-2700. PMID 22380704.
|This article about analytical chemistry is a stub. You can help Wikipedia by expanding it.|