Surfactant protein C
|Surfactant protein C, N terminal propeptide|
Pulmonary surfactant-associated polypeptide SP-C Protein
|surfactant, pulmonary-associated protein C|
|Locus||Chr. 8 p21|
Surfactant proteins C are a family of related pulmonary surfactant proteins.
The propeptide of human protein from this family has an N-terminal alpha-helical segment whose suggested function was stabilization of the protein structure, since the latter can irreversibly transform from its native alpha-helical structure to beta-sheet aggregates and form amyloid fibrils. The correct intracellular trafficking of proSP-C has also been reported to depend on the propeptide.
- Pulmonary Surfactant-Associated Protein C at the US National Library of Medicine Medical Subject Headings (MeSH)