A sustentacular cell is a type of cell primarily associated with structural support.
About 40% of carcinoids have a scattering of sustentacular cells, which stain positive for S-100.
Sustentacular cells are supporting cells of the seminiferous tubules of the testis, responsible for the differentiation of spermatids, the maintenance of the blood-testis barrier, and the secretion of inhibin, androgen-binding protein, and Mullerian-inhibiting factor.
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