According to the 1930 census, 1,608 Jews lived in Târgu Frumos. In the fall of 1940, all Jewish men, from 18 to 50 years old, were subjected to forced labor. Many were sent to the work camp Tudoreni-Rechita, situated in Botoșani County, while others were deported to Transnistria. Târgu Frumos was also a 24-hour stop of the "Death train" going to the Călărași camp. On July 1, 1941, when the train arrived in Târgu Frumos, 654 bodies were removed from the train and transported to the local Jewish cemetery where they were buried.