T cell vaccination is immunization with inactivated autoreactive T cells. The concept of T cell vacination is, at least partially, analogous to classical vaccination against infectious disease. However, the agents to be eliminated or neutralized are not foreign microbial agents but a pathogenic autoreactive T cell population. Research on T cell vaccination so far has focused mostly on multiple sclerosis and to a lesser extent on rheumatoid arthritis, Crohn's disease and AIDS.
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- Zhang J (2002). "T-cell vaccination for autoimmune diseases: immunologic lessons and clinical experience in multiple sclerosis". Expert Rev Vaccines. 1 (3): 285–92. doi:10.1586/14760522.214.171.1245. PMID 12901569.
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