T12 may refer to:
- T12 lamps are a kind of fluorescent light format
- T-12 antitank gun, a Russian weapon
- T-12 Cloudmaker, a super heavy demolition bomb
- T-12 sniper rifle, a Turkish weapon
- T-12 tank, a medium tank and prototype of the T-24
- Thoracic spinal nerve 12
- Twelfth thoracic vertebra
- Trikke 12 Roadstar, a 3-wheeled cambering vehicle
- Telstar 12, a broadcast satellite
- T12, a 12⁄8-inch-diameter fluorescent lamp format
- T12, the bacteriophage responsible for scarlet fever
- Monzen-Nakachō Station of the Tokyo Metro (station number T-12/E-15)
- T12 (classification), visual impairment category for disability track and field athletics
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