Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit associated with a subset of TFIID complexes. This subunit interacts with TBP and with two other small subunits of TFIID, TAF10 and TAF11. There is a pseudogene located on chromosome 6.
^Birck C, Poch O, Romier C, Ruff M, Mengus G, Lavigne AC et al. (Jul 1998). "Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family". Cell94 (2): 239–49. doi:10.1016/S0092-8674(00)81423-3. PMID9695952.
Parada CA, Yoon JB, Roeder RG (1995). "A novel LBP-1-mediated restriction of HIV-1 transcription at the level of elongation in vitro". J. Biol. Chem.270 (5): 2274–83. doi:10.1074/jbc.270.5.2274. PMID7836461.
Kashanchi F, Piras G, Radonovich MF, Duvall JF, Fattaey A, Chiang CM et al. (1994). "Direct interaction of human TFIID with the HIV-1 transactivator tat". Nature367 (6460): 295–9. doi:10.1038/367295a0. PMID8121496.
Wang Z, Morris GF, Rice AP, Xiong W, Morris CB (1996). "Wild-type and transactivation-defective mutants of human immunodeficiency virus type 1 Tat protein bind human TATA-binding protein in vitro". J. Acquir. Immune Defic. Syndr. Hum. Retrovirol.12 (2): 128–38. doi:10.1097/00042560-199606010-00005. PMID8680883.
García-Martínez LF, Ivanov D, Gaynor RB (1997). "Association of Tat with purified HIV-1 and HIV-2 transcription preinitiation complexes". J. Biol. Chem.272 (11): 6951–8. doi:10.1074/jbc.272.11.6951. PMID9054383.
Dantonel JC, Murthy KG, Manley JL, Tora L (1997). "Transcription factor TFIID recruits factor CPSF for formation of 3' end of mRNA". Nature389 (6649): 399–402. doi:10.1038/38763. PMID9311784.
Birck C, Poch O, Romier C, Ruff M, Mengus G, Lavigne AC et al. (1998). "Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family". Cell94 (2): 239–49. doi:10.1016/S0092-8674(00)81423-3. PMID9695952.
Imabayashi H, Mori T, Gojo S, Kiyono T, Sugiyama T, Irie R et al. (2003). "Redifferentiation of dedifferentiated chondrocytes and chondrogenesis of human bone marrow stromal cells via chondrosphere formation with expression profiling by large-scale cDNA analysis". Exp. Cell Res.288 (1): 35–50. doi:10.1016/S0014-4827(03)00130-7. PMID12878157.