TAF4B

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TAF4B
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases TAF4B, SPGF13, TAF2C2, TAFII105, TATA-box binding protein associated factor 4b
External IDs MGI: 2152345 HomoloGene: 28266 GeneCards: TAF4B
RNA expression pattern
PBB GE TAF4B gnf1h09648 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001293725
NM_005640

NM_001100449

RefSeq (protein)

NP_001280654
NP_005631

NP_001093919.1
NP_001093919

Location (UCSC) Chr 18: 26.23 – 26.39 Mb Chr 18: 14.78 – 14.9 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Transcription initiation factor TFIID subunit 4B is a protein that in humans is encoded by the TAF4B gene.[3][4][5]

Function[edit]

TATA-binding protein associated factors (TAFs) participate, with TATA binding protein (TBP; MIM 600075), in the formation of the TFIID protein complex (see MIM 313650), which is involved in the initiation of gene transcription by RNA polymerase II (see MIM 180660).[supplied by OMIM][5]

Interactions[edit]

TAF4B has been shown to interact with RELA.[6]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Dikstein R, Zhou S, Tjian R (Nov 1996). "Human TAFII 105 is a cell type-specific TFIID subunit related to hTAFII130". Cell. 87 (1): 137–46. doi:10.1016/S0092-8674(00)81330-6. PMID 8858156. 
  4. ^ Yamit-Hezi A, Nir S, Wolstein O, Dikstein R (Jul 2000). "Interaction of TAFII105 with selected p65/RelA dimers is associated with activation of subset of NF-kappa B genes". J. Biol. Chem. 275 (24): 18180–7. doi:10.1074/jbc.275.24.18180. PMID 10849440. 
  5. ^ a b "Entrez Gene: TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa". 
  6. ^ Yamit-Hezi A, Dikstein R (Sep 1998). "TAFII105 mediates activation of anti-apoptotic genes by NF-kappaB". EMBO J. 17 (17): 5161–9. doi:10.1093/emboj/17.17.5161. PMC 1170844Freely accessible. PMID 9724652. 

Further reading[edit]