TFAP4

From Wikipedia, the free encyclopedia
Jump to: navigation, search
TFAP4
Identifiers
Aliases TFAP4, AP-4, bHLHc41, transcription factor AP-4 (activating enhancer binding protein 4)
External IDs MGI: 103239 HomoloGene: 2424 GeneCards: 7023
RNA expression pattern
PBB GE TFAP4 205688 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003223

NM_031182

RefSeq (protein)

NP_003214.1

n/a

Location (UCSC) Chr 16: 4.26 – 4.27 Mb Chr 16: 4.54 – 4.56 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Transcription factor AP-4 (activating enhancer binding protein 4), also known as TFAP4, is a protein which in humans is encoded by the TFAP4 gene.[1]

Function[edit]

Transcription factor AP4 is a member of the basic helix-loop-helix (bHLH) transcription factors, which bind to the E-box sequence in the promoters of their target genes. AP-4 has been shown to act both as a repressor and an activator for different target genes.

References[edit]

Further reading[edit]

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.