TGF beta 2

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TGFB2
Protein TGFB2 PDB 1tfg.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases TGFB2, LDS4, TGF-beta2, transforming growth factor beta 2, G-TSF
External IDs OMIM: 190220 MGI: 98726 HomoloGene: 2432 GeneCards: TGFB2
Gene location (Human)
Chromosome 1 (human)
Chr. Chromosome 1 (human)[1]
Chromosome 1 (human)
Genomic location for TGFB2
Genomic location for TGFB2
Band 1q41 Start 218,346,235 bp[1]
End 218,444,619 bp[1]
RNA expression pattern
PBB GE TGFB2 209909 s at fs.png

PBB GE TGFB2 209908 s at fs.png

PBB GE TGFB2 220407 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003238
NM_001135599

NM_009367
NM_001329107

RefSeq (protein)

NP_001129071
NP_003229

NP_001316036
NP_033393

Location (UCSC) Chr 1: 218.35 – 218.44 Mb Chr 1: 186.62 – 186.71 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Transforming growth factor-beta 2 (TGF-β2) is a secreted protein known as a cytokine that performs many cellular functions and has a vital role during embryonic development (alternative names: Glioblastoma-derived T-cell suppressor factor, G-TSF, BSC-1 cell growth inhibitor, Polyergin, Cetermin). It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. There are two named isoforms of this protein, created by alternative splicing of the same gene.

Further reading[edit]