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Historically all rooms in the hotel were suites of at least 750 square feet (70 m2). The suites are composed of two rooms. Floors 39-41 (marked 60-62 in elevators) house Penthouses, which range from 1,500 to 2,500 square feet (140 to 230 m2). There is also a single Presidential Suite, named "HP", that is over 4,500 sq ft (420 m2). There are also "deluxe" suites which are available to guests. While similar in style to traditional hotel rooms (single room), they are located on the Penthouse level and feature upgraded sheets, bath products and other amenities not found in the standard suites below.
In 2006, the lettering at the top of the tower changed to "THEhotel" to distinguish the property. Formerly, the lettering was identical to the "Mandalay Bay" letters at the top of the original tower.
On August 6, 2012, MGM Resorts International announced the rebranding of THEhotel into the Delano Las Vegas. All of the 1,100 suites at the hotel will be redesigned. There will be new bars, lounges, restaurants and nightclubs.