THRSP

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THRSP
Identifiers
AliasesTHRSP, LPGP1, Lpgp, S14, SPOT14, THRP, thyroid hormone responsive
External IDsMGI: 109126 HomoloGene: 2441 GeneCards: THRSP
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for THRSP
Genomic location for THRSP
Band11q14.1Start78,063,861 bp[1]
End78,068,351 bp[1]
RNA expression pattern
PBB GE THRSP gnf1h00039 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003251

NM_009381

RefSeq (protein)

NP_003242

NP_033407

Location (UCSC)Chr 11: 78.06 – 78.07 MbChr 7: 97.41 – 97.42 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Thyroid hormone-inducible hepatic protein is a protein that in humans is encoded by the THRSP gene.[5][6]

The protein encoded by this gene is similar to the gene product of S14, a rat gene whose expression is limited to liver and adipose tissue and is controlled by nutritional and hormonal factors. This gene has been shown to be expressed in liver and adipocytes, particularly in lipomatous modules. It is also found to be expressed in lipogenic breast cancers, which suggests a role in controlling tumor lipid metabolism.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000151365 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000035686 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ Grillasca JP, Gastaldi M, Khiri H, Dace A, Peyrol N, Reynier P, Torresani J, Planells R (Feb 1997). "Cloning and initial characterization of human and mouse Spot 14 genes". FEBS Lett. 401 (1): 38–42. doi:10.1016/S0014-5793(96)01433-0. PMID 9003802.
  6. ^ a b "Entrez Gene: THRSP thyroid hormone responsive (SPOT14 homolog, rat)".

Further reading[edit]