TL-1238

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TL-1238
TL-1238.svg
Names
IUPAC name
3-[(Dimethylcarbamoyl)oxy]-N,N-diethyl-N-methylanilinium iodide
Other names
Substance 3393
Identifiers
3D model (JSmol)
ChemSpider
Properties
C14H23IN2O2
Molar mass 378.254 g·mol−1
Hazards
Main hazards Extremely toxic
Lethal dose or concentration (LD, LC):
60 μg/kg (mice, intravenous)[1]
175 μg/kg (mice, subcutaneous)[1]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

TL-1238 (Substance 3393) is an extremely potent carbamate acetylcholinesterase inhibitor. It has been shown to be more potent than neostigmine.[2][3]

See also[edit]

References[edit]

  1. ^ a b "ChemIDplus".
  2. ^ Bülbring, E; Chou, TC (March 1947). "The relative activity of prostigmine homologues and other substances as antagonists to tubocurarine". British Journal of Pharmacology and Chemotherapy. 2 (1): 8–22. doi:10.1111/j.1476-5381.1947.tb00316.x. PMC 1509759. PMID 19108106.
  3. ^ BLASCHKO, H; BULBRING, E; CHOU, TC (March 1949). "Tubocurarine antagonism and inhibition of cholinesterases". British Journal of Pharmacology and Chemotherapy. 4 (1): 29–32. doi:10.1111/j.1476-5381.1949.tb00512.x. PMC 1509899. PMID 18113150.