TMPRSS6

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TMPRSS6
Identifiers
AliasesTMPRSS6, IRIDA, transmembrane protease, serine 6, matriptase-2, transmembrane serine protease 6
External IDsMGI: 1919003 HomoloGene: 12408 GeneCards: TMPRSS6
Gene location (Human)
Chromosome 22 (human)
Chr.Chromosome 22 (human)[1]
Chromosome 22 (human)
Genomic location for TMPRSS6
Genomic location for TMPRSS6
Band22q12.3Start37,065,436 bp[1]
End37,109,563 bp[1]
RNA expression pattern
PBB GE TMPRSS6 214955 at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001289000
NM_001289001
NM_153609

NM_027902
NM_001355601

RefSeq (protein)

NP_001275929
NP_001275930
NP_705837

NP_082178
NP_001342530

Location (UCSC)Chr 22: 37.07 – 37.11 MbChr 15: 78.44 – 78.47 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Transmembrane protease, serine 6 (also known as matriptase-2) is an enzyme that in humans is encoded by the TMPRSS6 gene.[5]

The protein encoded by this gene is a type II transmembrane serine proteinase that is found attached to the cell surface. The encoded protein may be involved in matrix remodeling processes in the liver.[5]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000187045 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000016942 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:".
  4. ^ "Mouse PubMed Reference:".
  5. ^ a b "Entrez Gene: TMPRSS6 transmembrane protease, serine 6".

Further reading[edit]