TNFRSF19

From Wikipedia, the free encyclopedia
Jump to: navigation, search
TNFRSF19
Identifiers
Aliases TNFRSF19, TAJ, TAJ-alpha, TRADE, TROY, tumor necrosis factor receptor superfamily member 19
External IDs MGI: 1352474 HomoloGene: 8481 GeneCards: 55504
Genetically Related Diseases
Disease Name References
nasopharyngeal carcinoma
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001204458
NM_001204459
NM_018647
NM_148957

NM_001164155
NM_013869

RefSeq (protein)

NP_001191387.1
NP_001191388.1
NP_061117.2
NP_683760.1

NP_001157627.1
NP_038897.4

Location (UCSC) Chr 13: 23.57 – 23.68 Mb Chr 14: 60.96 – 61.05 Mb
PubMed search [2] [3]
Wikidata
View/Edit Human View/Edit Mouse

Tumor necrosis factor receptor superfamily, member 19, also known as TNFRSF19 and TROY is a human gene.[1]

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively, spliced transcript variants encoding distinct isoforms have been described.[1]

References[edit]

Further reading[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.