TNS1

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TNS1
Identifiers
Aliases TNS1, MST091, MST122, MST127, MSTP122, MSTP127, MXRA6, PPP1R155, TNS, MSTP091, tensin 1
External IDs MGI: 104552 HomoloGene: 11219 GeneCards: TNS1
RNA expression pattern
PBB GE TNS1 218864 at fs.png

PBB GE TNS1 221246 x at fs.png

PBB GE TNS1 218863 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001308022
NM_001308023
NM_022648

NM_001289895
NM_027884
NM_177169

RefSeq (protein)

NP_001294951
NP_001294952
NP_072174
NP_001294951.1
NP_001294952.1

n/a

Location (UCSC) Chr 2: 217.8 – 218 Mb Chr 1: 73.91 – 74.12 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Tensin-1 is a protein that in humans is encoded by the TNS1 gene.[3]

The protein encoded by this gene localizes to focal adhesions, regions of the plasma membrane where the cell attaches to the extracellular matrix. This protein crosslinks actin filaments and contains a Src homology 2 (SH2) domain, which is often found in molecules involved in signal transduction. This protein is a substrate of calpain II. A second transcript from this gene has been described, but its full length nature has not been determined.[3]

References[edit]

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