TOB2

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TOB2
Identifiers
Aliases TOB2, TOB4, TOBL, TROB2, transducer of ERBB2, 2, APRO5
External IDs MGI: 1888525 HomoloGene: 9447 GeneCards: TOB2
RNA expression pattern
PBB GE TOB2 222243 s at fs.png

PBB GE TOB2 221496 s at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_016272

NM_020507

RefSeq (protein)

NP_057356

NP_065253.1
NP_065253

Location (UCSC) Chr 22: 41.43 – 41.45 Mb Chr 15: 81.85 – 81.86 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Protein Tob2 is a protein that in humans is encoded by the TOB2 gene.[3][4][5]

TOB2 belongs to the TOB (see TOB1; MIM 605523)/BTG1 (MIM 109580) family of antiproliferative proteins, which are involved in the regulation of cell cycle progression.[supplied by OMIM][5]

Interactions[edit]

TOB2 has been shown to interact with CNOT7.[3]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ a b Ikematsu N, Yoshida Y, Kawamura-Tsuzuku J, Ohsugi M, Onda M, Hirai M, Fujimoto J, Yamamoto T (Jan 2000). "Tob2, a novel anti-proliferative Tob/BTG1 family member, associates with a component of the CCR4 transcriptional regulatory complex capable of binding cyclin-dependent kinases". Oncogene. 18 (52): 7432–41. doi:10.1038/sj.onc.1203193. PMID 10602502. 
  4. ^ Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP, et al. (Dec 1999). "The DNA sequence of human chromosome 22". Nature. 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208. 
  5. ^ a b "Entrez Gene: TOB2 transducer of ERBB2, 2". 

Further reading[edit]