TOMM34

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TOMM34
Identifiers
Aliases TOMM34, HTOM34P, TOM34, URCC3, translocase of outer mitochondrial membrane 34
External IDs MGI: 1914395 HomoloGene: 4956 GeneCards: TOMM34
Gene location (Human)
Chromosome 20 (human)
Chr. Chromosome 20 (human)[1]
Chromosome 20 (human)
Genomic location for TOMM34
Genomic location for TOMM34
Band 20q13.12 Start 44,942,130 bp[1]
End 44,960,486 bp[1]
RNA expression pattern
PBB GE TOMM34 201870 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_006809

NM_001291155
NM_025996

RefSeq (protein)

NP_006800

NP_001278084
NP_080272

Location (UCSC) Chr 20: 44.94 – 44.96 Mb Chr 2: 164.05 – 164.07 Mb
PubMed search [3] [4]
Wikidata
View/Edit Human View/Edit Mouse

Mitochondrial import receptor subunit TOM34 is a protein that in humans is encoded by the TOMM34 gene.[5][6]

The protein encoded by this gene is involved in the import of precursor proteins into mitochondria. The encoded protein has a chaperone-like activity, binding the mature portion of unfolded proteins and aiding their import into mitochondria. This protein, which is found in the cytoplasm and sometimes associated with the outer mitochondrial membrane, has a weak ATPase activity and contains 6 TPR repeats.[6]

References[edit]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000025772 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000018322 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Nuttall SD, Hanson BJ, Mori M, Hoogenraad NJ (Oct 1997). "hTom34: a novel translocase for the import of proteins into human mitochondria". DNA Cell Biol. 16 (9): 1067–74. doi:10.1089/dna.1997.16.1067. PMID 9324309. 
  6. ^ a b "Entrez Gene: TOMM34 translocase of outer mitochondrial membrane 34". 

Further reading[edit]