P24 protein family
|P24 protein family|
P24 protein family is a group of transmembrane proteins that are major components of COPI and COPII-coated vesicles. The family is also known as EMP24/GP25L/p24 family and TMP21-like proteins. The latter naming was after transmembrane emp24 domain-containing protein 10 that was found in the human brain. It was claimed to block the beta-amyloid peptide, which is implicated in the pathogenesis of Alzheimer's Disease.
- Protein blocks Alzheimer's toxins in lab tests. CBC News Posted: Apr 27, 2006 1:46 PM ET
- "TMP21 is a presenilin complex component that modulates - but not e-secretase activity." Nature 440: 1208-12.