TRAP1

From Wikipedia, the free encyclopedia
Jump to: navigation, search
TRAP1
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases TRAP1, HSP 75, HSP75, HSP90L, TRAP-1, TNF receptor associated protein 1
External IDs MGI: 1915265 HomoloGene: 9457 GeneCards: 10131
RNA expression pattern
PBB GE TRAP1 201391 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001272049
NM_016292

NM_026508

RefSeq (protein)

NP_001258978.1
NP_057376.2

NP_080784.1

Location (UCSC) Chr 16: 3.65 – 3.72 Mb Chr 16: 4.04 – 4.08 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Heat shock protein 75 kDa, mitochondrial is a protein that in humans is encoded by the TRAP1 gene.[3][4][5]


Interactions[edit]

TRAP1 has been shown to interact with EXT2,[6] EXT1[6] and Retinoblastoma protein.[7]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Felts SJ, Owen BA, Nguyen P, Trepel J, Donner DB, Toft DO (March 2000). "The hsp90-related protein TRAP1 is a mitochondrial protein with distinct functional properties". J Biol Chem. 275 (5): 3305–12. doi:10.1074/jbc.275.5.3305. PMID 10652318. 
  4. ^ Song HY, Dunbar JD, Zhang YX, Guo D, Donner DB (March 1995). "Identification of a protein with homology to hsp90 that binds the type 1 tumor necrosis factor receptor". J Biol Chem. 270 (8): 3574–81. doi:10.1074/jbc.270.8.3574. PMID 7876093. 
  5. ^ "Entrez Gene: TRAP1 TNF receptor-associated protein 1". 
  6. ^ a b Simmons, A D; Musy M M; Lopes C S; Hwang L Y; Yang Y P; Lovett M (November 1999). "A direct interaction between EXT proteins and glycosyltransferases is defective in hereditary multiple exostoses". Hum. Mol. Genet. ENGLAND. 8 (12): 2155–64. doi:10.1093/hmg/8.12.2155. ISSN 0964-6906. PMID 10545594. 
  7. ^ Chen, C F; Chen Y; Dai K; Chen P L; Riley D J; Lee W H (September 1996). "A new member of the hsp90 family of molecular chaperones interacts with the retinoblastoma protein during mitosis and after heat shock". Mol. Cell. Biol. UNITED STATES. 16 (9): 4691–9. ISSN 0270-7306. PMC 231469free to read. PMID 8756626. 

Further reading[edit]

External links[edit]