TRERF1

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TRERF1
Identifiers
Aliases TRERF1, BCAR2, HSA277276, RAPA, TREP132, TReP-132, dJ139D8.5, transcriptional regulating factor 1
External IDs MGI: 2442086 HomoloGene: 14129 GeneCards: TRERF1
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001297573
NM_018415
NM_033501
NM_033502

NM_001097623
NM_172622

RefSeq (protein)

NP_001284502
NP_277037

NP_001091092.1
NP_766210.1
NP_001091092
NP_766210

Location (UCSC) Chr 6: 42.22 – 42.45 Mb n/a
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Transcriptional-regulating factor 1 is a protein that in humans is encoded by the TRERF1 gene.[3][4]

This gene encodes a zinc-finger transcriptional regulating protein that interacts with CBP/p300 to regulate the human gene CYP11A1.[4]

Interactions[edit]

TRERF1 has been shown to interact with Steroidogenic factor 1,[5] EP300[3] and CREB-binding protein.[3]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ a b c Gizard F, Lavallee B, DeWitte F, Hum DW (Sep 2001). "A novel zinc finger protein TReP-132 interacts with CBP/p300 to regulate human CYP11A1 gene expression". J Biol Chem. 276 (36): 33881–92. doi:10.1074/jbc.M100113200. PMID 11349124. 
  4. ^ a b "Entrez Gene: TRERF1 transcriptional regulating factor 1". 
  5. ^ Gizard, Florence; Lavallee Bernard; DeWitte Frederique; Teissier Elisabeth; Staels Bart; Hum Dean W (Oct 2002). "The transcriptional regulating protein of 132 kDa (TReP-132) enhances P450scc gene transcription through interaction with steroidogenic factor-1 in human adrenal cells". J. Biol. Chem. United States. 277 (42): 39144–55. doi:10.1074/jbc.M205786200. ISSN 0021-9258. PMID 12101186. 

Further reading[edit]