TRIM29

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TRIM29
Protein TRIM29 PDB 2csv.png
Available structures
PDB Ortholog search: PDBe RCSB
Identifiers
Aliases TRIM29, ATDC, tripartite motif containing 29
External IDs MGI: 1919419 HomoloGene: 8100 GeneCards: TRIM29
RNA expression pattern
PBB GE TRIM29 211002 s at fs.png

PBB GE TRIM29 211001 at fs.png

PBB GE TRIM29 202504 at fs.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_012101
NM_058193
NM_001330382

NM_023655

RefSeq (protein)

NP_001317311
NP_036233

NP_076144.2
NP_076144

Location (UCSC) Chr 11: 120.11 – 120.19 Mb Chr 9: 43.31 – 43.34 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Tripartite motif-containing protein 29 is a protein that in humans is encoded by the TRIM29 gene.[3][4]

Function[edit]

The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype.[4]

Interactions[edit]

TRIM29 has been shown to interact with TRIM23[3] and GCC1.[5]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ a b Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci S, Pelicci PG, Ballabio A (May 2001). "The tripartite motif family identifies cell compartments". EMBO J. 20 (9): 2140–51. doi:10.1093/emboj/20.9.2140. PMC 125245Freely accessible. PMID 11331580. 
  4. ^ a b "Entrez Gene: TRIM29 tripartite motif-containing 29". 
  5. ^ Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. 

Further reading[edit]