TRIM6

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TRIM6
Identifiers
Aliases TRIM6, RNF89, tripartite motif containing 6
External IDs MGI: 2137352 HomoloGene: 14381 GeneCards: TRIM6
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_058166
NM_001003818
NM_001198644
NM_001198645

NM_001013616

RefSeq (protein)

NP_001003818
NP_001185573
NP_001185574
NP_477514

NP_001013637.1
NP_001013637

Location (UCSC) Chr 11: 5.6 – 5.61 Mb Chr 7: 104.22 – 104.24 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Tripartite motif-containing protein 6 is a protein that in humans is encoded by the TRIM6 gene.[3][4]

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the nucleus, but its specific function has not been identified. This gene is mapped to chromosome 11p15, where it resides within a TRIM gene cluster. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. A read-through transcript transcribed from this gene and TRIM34 has been observed.[4]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci S, Pelicci PG, Ballabio A (May 2001). "The tripartite motif family identifies cell compartments". EMBO J. 20 (9): 2140–51. doi:10.1093/emboj/20.9.2140. PMC 125245Freely accessible. PMID 11331580. 
  4. ^ a b "Entrez Gene: TRIM6 tripartite motif-containing 6". 

Further reading[edit]