TRIP11

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TRIP11
Identifiers
Aliases TRIP11, ACG1A, CEV14, GMAP-210, TRIP-11, TRIP230, GMAP210, thyroid hormone receptor interactor 11
External IDs MGI: 1924393 HomoloGene: 20897 GeneCards: TRIP11
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_004239
NM_001321851

NM_028446

RefSeq (protein)

NP_001308780
NP_004230

n/a

Location (UCSC) Chr 14: 91.97 – 92.04 Mb Chr 12: 101.83 – 101.91 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Thyroid receptor-interacting protein 11 is a protein that in humans is encoded by the TRIP11 gene.[3][4][5]

Function[edit]

TRIP11 was first identified through its ability to interact functionally with thyroid hormone receptor-beta (THRB; MIM 190160). It has also been found in association with the Golgi apparatus and microtubules.[supplied by OMIM][5]

Interactions[edit]

TRIP11 has been shown to interact with Retinoblastoma protein[6] and Thyroid hormone receptor alpha.[6]

References[edit]

  1. ^ "Human PubMed Reference:". 
  2. ^ "Mouse PubMed Reference:". 
  3. ^ Lee JW, Choi HS, Gyuris J, Brent R, Moore DD (Feb 1995). "Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor". Molecular Endocrinology. 9 (2): 243–54. doi:10.1210/me.9.2.243. PMID 7776974. 
  4. ^ Abe A, Emi N, Tanimoto M, Terasaki H, Marunouchi T, Saito H (Dec 1997). "Fusion of the platelet-derived growth factor receptor beta to a novel gene CEV14 in acute myelogenous leukemia after clonal evolution". Blood. 90 (11): 4271–7. PMID 9373237. 
  5. ^ a b "Entrez Gene: TRIP11 thyroid hormone receptor interactor 11". 
  6. ^ a b Chang KH, Chen Y, Chen TT, Chou WH, Chen PL, Ma YY, Yang-Feng TL, Leng X, Tsai MJ, O'Malley BW, Lee WH (Aug 1997). "A thyroid hormone receptor coactivator negatively regulated by the retinoblastoma protein". Proceedings of the National Academy of Sciences of the United States of America. 94 (17): 9040–5. doi:10.1073/pnas.94.17.9040. PMC 23019Freely accessible. PMID 9256431. 

Further reading[edit]