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Transient receptor potential cation channel, subfamily C, member 3
Symbols TRPC3 ; TRP3
External IDs OMIM602345 MGI109526 HomoloGene20708 IUPHAR: 488 GeneCards: TRPC3 Gene
RNA expression pattern
PBB GE TRPC3 206425 s at tn.png
PBB GE TRPC3 210814 at tn.png
More reference expression data
Species Human Mouse
Entrez 7222 22065
Ensembl ENSG00000138741 ENSMUSG00000027716
UniProt Q13507 B1ATV3
RefSeq (mRNA) NM_001130698 NM_019510
RefSeq (protein) NP_001124170 NP_062383
Location (UCSC) Chr 4:
122.8 – 122.87 Mb
Chr 3:
36.62 – 36.69 Mb
PubMed search [1] [2]

Transient receptor potential cation channel, subfamily C, member 3, also known as TRPC3, is a human gene encoding a protein of the same name.


TRPC3 has been shown to interact with TRPC1[1][2] and TRPC6.[3]

See also[edit]

Further reading[edit]

  • Islam, Md. Shahidul (January 2011). Transient Receptor Potential Channels. Advances in Experimental Medicine and Biology 704. Berlin: Springer. p. 700. ISBN 978-94-007-0264-6. 
  • Lemmon MA (2005). "Pleckstrin homology domains: two halves make a hole?". Cell 120 (5): 574–6. doi:10.1016/j.cell.2005.02.023. PMID 15766521. 
  • Clapham DE, Julius D, Montell C, Schultz G (2006). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.". Pharmacol. Rev. 57 (4): 427–50. doi:10.1124/pr.57.4.6. PMID 16382100. 
  • Eder P, Poteser M, Groschner K (2007). "TRPC3: a multifunctional, pore-forming signalling molecule.". Handb Exp Pharmacol. Handbook of Experimental Pharmacology 179 (179): 77–92. doi:10.1007/978-3-540-34891-7_4. ISBN 978-3-540-34889-4. PMID 17217051.  |chapter= ignored (help)Eur J Neurosci. 2010 Apr;31(7):1219-32. Epub 2010 Mar 19.


  1. ^ Strübing, Carsten; Krapivinsky Grigory; Krapivinsky Luba; Clapham David E (Oct 2003). "Formation of novel TRPC channels by complex subunit interactions in embryonic brain". J. Biol. Chem. (United States) 278 (40): 39014–9. doi:10.1074/jbc.M306705200. ISSN 0021-9258. PMID 12857742. 
  2. ^ Xu, X Z; Li H S; Guggino W B; Montell C (Jun 1997). "Coassembly of TRP and TRPL produces a distinct store-operated conductance". Cell (UNITED STATES) 89 (7): 1155–64. doi:10.1016/S0092-8674(00)80302-5. ISSN 0092-8674. PMID 9215637. 
  3. ^ Hofmann, Thomas; Schaefer Michael; Schultz Günter; Gudermann Thomas (May 2002). "Subunit composition of mammalian transient receptor potential channels in living cells". Proc. Natl. Acad. Sci. U.S.A. (United States) 99 (11): 7461–6. doi:10.1073/pnas.102596199. ISSN 0027-8424. PMC 124253. PMID 12032305. 

External links[edit]

This article incorporates text from the United States National Library of Medicine, which is in the public domain.