Tryptic soy-serum-bacitracin-vancomycin

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TSBV is the acronym for tryptic soy-serum-bacitracin-vancomycin, a type of agar plate medium used in microbiological testing to select for Aggregatibacter actinomycetemcomitans (A.a.).[1] It was described by Jørgen Slots in 1982, who also discovered the role of A.a. in periodontitis.[2]

Per liter, TSBV contains:[3]

  • 40 g tryptic soy agar
  • 1 g yeast extract
  • 100 mL horse serum
  • 75 mg bacitracin
  • 5 mg vancomycin


  1. ^ Tryptic Soy Serum Bacitracin Vancomycin Agar (TSBV)
  2. ^ van Steenbergen, TJM. "Comparison of Two Selective Media for Actinobacillus actinomycetemcomitans." J Clin Microbiol 1986;24:636-638.
  3. ^ Slots, J. "Selective medium for isolation of Actinobacillus actinomycetemcomitans." J Clin Microbiol 1982;15:606-609.