TSPAN6

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TSPAN6
Identifiers
Aliases TSPAN6, T245, TM4SF6, TSPAN-6, tetraspanin 6
External IDs MGI: 1926264 HomoloGene: 20700 GeneCards: 7105
RNA expression pattern
PBB GE TSPAN6 209108 at tn.png

PBB GE TSPAN6 209109 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001278740
NM_001278741
NM_001278742
NM_001278743
NM_003270

NM_019656

RefSeq (protein)

NP_001265672.1
NP_003261.1

n/a

Location (UCSC) Chr X: 100.63 – 100.64 Mb Chr X: 133.89 – 133.9 Mb
PubMed search [1] [2]
Wikidata
View/Edit Human View/Edit Mouse

Tetraspanin-6 is a protein that in humans is encoded by the TSPAN6 gene.[1][2]

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is highly similar in sequence to the transmembrane 4 superfamily member 2. The use of alternate polyadenylation sites has been found for this gene.[2]

References[edit]

  1. ^ Maeda K, Matsuhashi S, Hori K, Xin Z, Mukai T, Tabuchi K, Egashira M, Niikawa N (Dec 1998). "Cloning and characterization of a novel human gene, TM4SF6, encoding a protein belonging to the transmembrane 4 superfamily, and mapped to Xq22". Genomics 52 (2): 240–2. doi:10.1006/geno.1998.5415. PMID 9782095. 
  2. ^ a b "Entrez Gene: TSPAN6 tetraspanin 6". 

Further reading[edit]