Table of volume of distribution for drugs

From Wikipedia, the free encyclopedia
Jump to: navigation, search

This is a table of volume of distribution (Vd) for various medication. For comparison, those with a Vd L/kg body weight of less than 0.2 are mainly distributed in blood plasma, 0.2-0.7 mostly in the extracellular fluid and those with more than 0.7 are distributed throughout total body water.

Medication Vd L/kg body weight
heparin 0.05-0.1[1]
insulin 0.05-0.1[1]
warfarin 0.1-0.2[1]
sulfamethoxazole 0.1-0.2[1]
glibenclamide 0.1-0.2[1]
atenolol 0.1-0.2[1]
NXY-059 0.1-0.2[2]
tubocurarine 0.2-0.4[1]
theophylline 0.4-0.7[1]
ethanol 0.7-0.9[1]
neostigmine 0.7-0.9[1]
phenytoin 0.7-0.9[1]
methotrexate 1-2[1]
indometacin 1-2[1]
paracetamol 1-2[1]
diazepam 1-2[1]
lidocaine 1-2[1]
glyceryl nitrate 2-5[1]
morphine 2-5[1]
propranolol 2-5[1]
digoxin 2-5[1]
chlorpromazine 2-5[1]
nortriptyline 2-5[1]
chloroquine 200[2]

References & footnotes[edit]

  1. ^ a b c d e f g h i j k l m n o p q r s t u v Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4.  Page 103
  2. ^ a b Estimated with a body weight of 70 kg.