Talaporfin

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Talaporfin
Talaporfin.png
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration
IV
ATC code
  • none
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
Formula C38H41N5O9
Molar mass 711.76 g/mol
3D model (JSmol)
 NYesY (what is this?)  (verify)

Talaporfin (INN, also known as aspartyl chlorin, mono-L-aspartyl chlorin e6, NPe6, or LS11) is a photosensitizer used in photodynamic therapy (PDT).

It absorbs red light at 664-667 nm normally provided by a laser tuned to this wavelength.[1]

It was approved in Japan (in 2004) for PDT of lung cancer and marketed as Laserphyrin.[2]

It is trademarked as Aptocine by Light Sciences Oncology.[3]

References[edit]

  1. ^ http://journals.lww.com/jto/Fulltext/2006/06000/Photodynamic_Therapy__PDT__for_Lung_Cancers.18.aspx "Photodynamic Therapy (PDT) for Lung Cancers" 2006
  2. ^ http://meeting.ascopubs.org/cgi/content/abstract/24/18_suppl/7229 "Photodynamic therapy using Laserphyrin for centrally located early stage lung cancer" 2006
  3. ^ http://www.lsoncology.com/aptocine

Extracorporeal Photo-Immunotherapy for Circulating Tumor Cells