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|WikiProject Pharmacology||(Rated Start-class, Mid-importance)|
Removed isomer statement under law section
This is not the only diastereomer that is scheduled without another one being scheduled. Only dextromethamphetamine is scheduled and not levo which appears otc. — Preceding unsigned comment added by 126.96.36.199 (talk) 06:11, 16 April 2007 (UTC)
Anyone know why these use https? Washod 13:00, 3 May 2007 (UTC)
Mistake in chemistry?
4-methylaminorex exists as four stereoisomers - (±)-cis and (±)-trans. The (±)-cis isomers are the form used recreationally. The (±)-cis isomers are generally synthesized from dl-phenylpropanolamine in one step by cyclization with cyanogen bromide (sometimes prepared in situ by reacting sodium cyanide with bromine). Alternate synthesis routes generally involve more steps, such as replacing cyanogen bromide with sodium or potassium cyanate to form an intermediate and then reacting it with concentrated hydrochloric acid. The (±)-trans isomers are synthesized in the same manner above but dl-norpseudoephedrine is used as the starting material instead.
After my best of knowledge this is not correct. The synthesis with cyanogen bromide works on dl-norephedrine AND dl-norpseudoephedrine (thats actually dl-phenylpropanolamine by definition, but this got all pretty messed up for nobody follows definitions of chemical nomenclatura, except IUPAC). The synthesis with cyanate works on l-norephedrine (and maybe on d-norpseudoephedrine, but I am not sure about this). The mistake was probably caused by Rhodium posting his flawed perception of the stereochemistry (he was never much of a chemist). This flawed version was lateron corrected by himself but it was IIRC still included in the latest downloadable version of Rhodiums page before it went offline.
Media dispersal of incorrect terminology, and this Wiki
The section stating "Methamphetamine is more commonly called Ice" is somewhat misleading. While this is the case, this is due to the confusion by reporters when 4MA first became prevalent in communities and was being termed "Ice", while everyone knew Methamphetamine (or glass) the term ice seemed to be associative with the Glass reference so it was taken this way. The danger of this is in the assertion that Ice is usually referring to meth, this would be the case in the lower echelons of the drug trade, but the fact is, ice is ice, glass is glass, they differ, when imported it will be referred to as Ice meaning 4MA. Someone please tidy this little bit up so not to perpetuate the misnomer usage of slang term Ice... Having worked with an ambulance company for a few years was enough for me to see "meth overdoses" that turned out the be people freaking out after taking 4MA they thought was meth due to the term "Ice" I'm not sure how to clean this section up on the terminology, but it really ought be. —Preceding unsigned comment added by 188.8.131.52 (talk) 19:27, 10 June 2008 (UTC)
I've removed the Weasel template since there's been no discussion or explanation. If anyone feels the need for this template, put it back up and justify it here. 184.108.40.206 (talk) 05:13, 3 September 2009 (UTC)
Using thiocyanate in place of cyanate yield 4MAR with a thiooxazoline ring - T-EU4EUH' as it were. See 'Reactivity of chlorodeoxypseudoephedrines with oxo-, thio-, and selenocyanates' by Cruz, Alejandro; Padilla-Martinez, Itzia Irene; Garcia-Baez, Efren V.; Contreras, Rosalinda. Tetrahedron: Asymmetry, 2007 , vol. 18, # 1 p. 123 - 130 — Preceding unsigned comment added by 220.127.116.11 (talk) 12:18, 17 November 2011 (UTC)
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