From Wikipedia, the free encyclopedia
How can agomelatine be listed as both an agonist and an antagonist?
- That must be an error? I am not a biochemist but one reference (M. J. Millan, A. Gobert, F. Lejeune, A. Dekeyne, A. Newman-Tancredi, V. Pasteau, J.-M. Rivet & D. Cussac (2003). "The novel melatonin agonist agomelatine (S20098) is an antagonist at 5-hydroxytryptamine2C receptors, blockade of which enhances the activity of frontocortical dopaminergic and adrenergic pathways". The Journal of pharmacology and experimental therapeutics. 306 (3): 954–954. doi:10.1124/jpet.103.051797. PMID 12750432. Unknown parameter
|month=ignored (help) ) calls it a melatonin agonist and a 2C antagonist, so I have erased agomelatine from the list of agonists. — fnielsen (talk) 10:02, 9 October 2008 (UTC)