Talk:Amino acid

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Good articleAmino acid has been listed as one of the Natural sciences good articles under the good article criteria. If you can improve it further, please do so. If it no longer meets these criteria, you can reassess it.
Article milestones
DateProcessResult
March 13, 2007Good article nomineeListed
November 3, 2008Good article reassessmentDelisted
November 18, 2008Good article nomineeListed
August 27, 2009Good article reassessmentKept
Current status: Good article

About AA's catabolic pathways[edit]

Regarding this piece: "After removal of one or more amino groups, the remainder of the molecule can sometimes be used to synthesize new amino acids, or it can be used for energy by entering glycolysis or the citric acid cycle, as detailed in image at right."

I think someone could add gluconeogenesis, at least, and maybe also the ketogenic pathways.

In fact, "the image at the right" puts it, so maybe someone could set it straight between text and image.

I also wasn't aware of aminoacids entering glycolysis, unless it was for gluconegoenesis, and the image on the right also doesn't show any support to it. In the end, it would be like: citric acid cycle, (glycolysis), ketogenesis, and gluconeogenesis

I just won't edit it by my own decision, I suppose.

--Orangutan45 (talk) 05:03, 24 May 2016 (UTC)

Zwiterionic AAs in the 21 AAs svg[edit]

Why are all the amino acids not shown in their zwitterionic forms in the main svg? At physiological 7.4 pH, this is what they would be, right? Moine Bouddhiste (talk) 12:28, 12 November 2016 (UTC)

Sure. But see #A question regarding the formulas, drawings and renditions among many other such discussions. DMacks (talk) 06:35, 14 November 2016 (UTC)

Missing positive charge on NH of imidazol ring of histidine[edit]

Should there not be a positive charge on the NH of the imidazol ring of histidine at physiological pH? — Preceding unsigned comment added by Moine Bouddhiste (talkcontribs) 14:08, 12 November 2016 (UTC)

The table says that its sidechain is 90% neutral, only 10% in the charged form. DMacks (talk) 06:34, 14 November 2016 (UTC)

proline as an imino acid[edit]

This is old terminology. According to the IUPAC Gold Book, an imino acid needs to have both imine and carboxyl functional groups. Proline instead has a secondary amine group. Double sharp (talk) 11:26, 26 November 2016 (UTC)

Agreed, and Amino acid#General structure looks like a good explanation of current and historical details. The other sections need to be brought in line to relegate "imino" to a secondary detail. DMacks (talk) 03:20, 27 November 2016 (UTC)
@Double sharp: as a starting point, do you agree with the §General structure statements? DMacks (talk) 03:32, 27 November 2016 (UTC)
Yes, that looks fine to me. Double sharp (talk) 03:58, 27 November 2016 (UTC)

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Lede needs a good edit[edit]

It's huge -- 555 words. That's surely too long. I don't have the interest or expertise, but hope someone else does. 60.248.185.19 (talk) 05:16, 1 June 2018 (UTC)

d-Amino Acids: Toxic or Not?[edit]

I'm not sure how or where to put it, but some explanation of how d-amino acids interact with multi-cellular biochemistry should be included. I have found various references to "d-amino acids are toxic to humans" on the internet, but none of them explain how. The sources I have found that say that are mostly abstracts for biochemical papers, so I assume they know what they are talking about. Nevertheless, this article does not even contain the statement "D-amino acids are toxic to most life" or its converse "d-amino acids are benign to most life". 66.219.236.172 (talk) 07:11, 8 July 2018 (UTC)

Neither of those statements is blanket true, and we certainly couldn't say so without a cite to a reliable source. Some D-amino acids might be toxic by certain routes of exposure. There is comparably little of it in our diet (based on low occurance due to difficulty in biosynthesis). But some D-amino acids are found naturally in us as part of major biochemical processes (as discussed in the article). Feel free to post links to some abstracts. DMacks (talk) 14:00, 8 July 2018 (UTC)