Talk:Anakinra

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Mechanism[edit]

The citation for this line "Anakinra differs from native human IL-1Ra in that it has the addition of a single methionine residue at its amino terminus" has a tooltip that is malformed, and I don't know how to fix it. — Preceding unsigned comment added by Regarr (talkcontribs) 21:48, 3 February 2016 (UTC)

kinneret x kineret[edit]

Hello... according to http://en.wikipedia.org/wiki/Kineret the drug has two n's. Can someone please double-check? In this article's intro sentence it has only one n. -- leuce (talk) 11:06, 13 March 2009 (UTC)

It has only one n. SteveD 7:31am 03-10-09 —Preceding unsigned comment added by 122.104.7.242 (talk) 21:31, 2 October 2009 (UTC)

Is it a DMARD[edit]

I'm not sure about the statement that it isn't a DMARD. From my readings it seems that there can be overlap between DMARDs and BRMs. The fact that it is a BRM distinguishes it from older non-specific medications like methotrexate, leflunomide, sulfasalazine, etc but it is still a DMARD because it is antirheumatic and slows the progression of the disease. I believe the American College of Rheumatology guidelines just calls it a biologic DMARD. 192.138.67.36 (talk)

pediatric use[edit]

Hey there! The article states that the pediatric use is contraindicated, but the prescribing information (http://www.kineretrx.com/fileadmin/user_upload/kineretus/documents/Kineret_Full_Prescribing_Information.pdf) states that it is indicated in NOMID (but not JRA) -> see section 8.4. I'm not sure how to add that information to the article.. Maybe a pharmacist here who can do that? mfg GierAffe — Preceding unsigned comment added by 62.2.176.4 (talk) 16:35, 9 May 2013 (UTC)

Is it still fda approved[edit]

I can't find any info if anakinra is still fda approved or not [[User:A915|A915]] a (talk) 19:02, 10 March 2014 (UTC)

what and when approved[edit]

Article does not say when FDA/EU etc approved it and any subsequent approvals. Article reads like an advert and copy of the package insert. Needs more inline cites. - Rod57 (talk) 11:36, 27 September 2016 (UTC)

UK NICE would not recommend in 2003[edit]

Final Appraisal Determination - Anakinra for rheumatoid arthritis. 2003 says "... anakinra is not recommended for the treatment of rheumatoid arthritis, except in the context of a controlled, long-term clinical study. ". Should mention ? - Rod57 (talk) 12:15, 27 September 2016 (UTC)