Talk:Astrocyte

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Untitled[edit]

A fantastic astrocyte pics is under copyright. I aked for permission to publish: NOT granted for free neither to pass the pics under GDFL. So, use the link only !

----- Message from ___.___@... -----
Date: Mon, 4 Oct 2004 10:16:56 +0200
Subject: RE: Educational use permission request - 92751A
To: Dennis Kunkel <kunkel@...>
Hello, For the picture usage, I don't know if I can afford the licence. If not, be asured your material will _not_ be used. Regards. Tom
----- Quoting Dennis Kunkel <kunkel@...> -----
> Date: Fri, 1 Oct 2004 07:00:20 -1000
> Subject: RE: Educational use permission request - 92751A
> To: ___.___@...
> Dear ___, As for use on wikipedia I would need to charge a small license for this non-profit use. The fee is $50 to use the image for unlimited time period. Using my copyright protected image and additional credit to my web site would be required. Please contact me if you have any additional questions. Regards, Dennis
> * Dennis Kunkel Ph.D.
> * Dennis Kunkel Microscopy, Inc.
> * PO Box 2008
> * Kailua, HI 96734
> * 808-263-0583
> * em ail - kunkel at denniskunkel dot com
> * web site - www.DennisKunkel.com
> ----- Original Message from: ___.___@... -----
> Sent: Friday, October 01, 2004 1:36 AM
> To: kunkel@...
> Subject: Educationnal use permission request - 92751A
> Dear Dennis, here is a permission request in email format:
> Email...............: ___.___@...
> First Name..........: __
> Last Name...........: ___
> Institue or school..: wikipedia.org
> Grade...............: none
> In the light box....: "92751A Astrocytic glial cell with cortical neuron"
> Project description.:
> Dear Dennis, the wikipedia is a not for profit project aiming at creating a free encyclopedia for all. A new article regarding astrocyte ceel got recently created. You could have a look at it at http://en.wikipedia.org/wiki/Astrocyte. I was looking for picture as an illustration and found your extraordinary one. So, I ask permission for a non-profit use of for example http://www.astrographics.com/GalleryPrints/Display/GP2016.jpg. Obviously the picture would be published with the full copyright notice, full credit to you, and your explicit written permission should you agree. To get a better feeling of permission asked you could see example http://en.wikipedia.org/wiki/Wikipedia:Boilerplate_request_for_permission. I am looking forward to hearing from you. Thank you for time and consideration. ___ ____.
----- End message -----

Discrepancy[edit]

A fundamental difference with neurons is their ability to duplicate through mitosis.

Is contradicted by the glial cell article. I'll remove unless someone confirms either way, then you can just plop it back in or put in that it they not undergo mitosis. -- Consumed Crustacean | Talk | 03:01, Jun 15, 2005 (UTC)


References[edit]

I think this article is severely lacking citation, there's no way this would be backed up in an academic context —Preceding unsigned comment added by Davidok1 (talkcontribs) 15:48, 19 May 2008 (UTC)

Image[edit]

The astrocyte/neuron picture in the link looks great, but its not very informative. The example of GFAP stained (green) cultured astrocytes on the article is more representitive of these cells, but ideally a golgi stained image, or an in situ (in tissue) two-photon image would be best as this shows the actual 3D morphology of these cells. (unsigned comment, 12/4/2006)

Agreed. The problem is that right now we don't have any such image freely available (see Wikipedia:Image use policy for context.) However, if you have the ability to make such an image, or the rights to one that exists, and you were willing to donate it, that would be greatly appreciated. --Arcadian 23:19, 4 December 2006 (UTC)
An in vivo in situ two-photon image has been added. 98.216.48.49 (talk) 23:25, 20 July 2008 (UTC)
In addition to the in vivo image a high resolution image would be nice; Mark Ellisman has some amazing images of the morphology of single astrocytes. Some picturs are here

http://www.jneurosci.org/cgi/content/full/22/1/183 This is free public access, can these images be added? Also search for "maryann martone astrocyte" in Google Image search. I think this group also has EM tomographic astrocyte reconstructions -- a good rendering of that would add a lot. —Preceding unsigned comment added by 98.216.48.49 (talk) 04:21, 4 May 2008 (UTC)

Neurogenesis?[edit]

What about the recent evidence that astrocytes play a role in post-natal neurogenesis? (example: Shetty et al., 2005 out of Duke U.) —Preceding unsigned comment added by 165.82.80.22 (talk) 15:40, 4 March 2008 (UTC)

copyvio[edit]

Note, I have deleted a part of the article that was copied from [1]. trespassers william (talk) 23:30, 8 March 2008 (UTC)

On Bergmann glia[edit]

In the main glia article, this subtype is listed under "radial glia". Does it really belong the the "Astrocyte" article? Is there a definitive source with classification of different subtypes? CopperKettle (talk) 16:13, 6 July 2008 (UTC)

Neurogenesis??[edit]

The section on astrocytes causing stem cells to transform into "working neurons" needs a citation. The question of whether new working neurons can be added to the adult brain is highly controversial. The current evidence strongly indicates that no new neurons can be added to the cortex in adulthood. If this section refers to the hippocampus only, that should be noted with the citation. Otherwise this section should be removed. 98.216.48.49 (talk) 23:25, 20 July 2008 (UTC)

Calcium waves[edit]

The entry should be updated to reflect recent work presented in Petravicz et al 2008 in the Journal of Neuroscience where it was shown that genetic removal of IP3 receptor type 2 blocks astrocyte Ca2+ increases. These mice were used in the cited Science paper by Agulhon et al. So far, no significant changes in synaptic transmission have been reported in these mice, which calls into question the validity of parts of the tripartite synapse model and the theory of gliotransmission. —Preceding unsigned comment added by 98.69.157.33 (talk) 04:40, 7 August 2010 (UTC)

new function[edit]

Astrocytes are no auxiliary cells. The neurons are doing and evaluate the energy astrocytes. Therefore, the amount and the ramifications. Straktur --Straktur (talk) 21:15, 15 January 2011 (UTC)

modified function[edit]

Astrocytes were listed as being able to reuptake neurotransmitters. The correct word would be uptake as reuptake is usually reserved for neurons reuptaking the neurotransmitter they have released themselves. Luke poa (talk) 13:53, 8 April 2011 (UTC)

Thanks for fixing it. Looie496 (talk) 17:49, 8 April 2011 (UTC)

Chronic pain sections[edit]

Astrocyte#Astrocytes in chronic pain sensitization and Astrocyte#Two states of persistent pain (added 4 May 2010) seem excessively detailed for this overview article. They could be translated into common English and merged into Chronic pain. This article probably only needs to say astrocyte activity has been implicated in the genesis and maintenance of some forms of chronic pain, and link to the more detailed info. Thoughts? --Anthonyhcole (talk) 03:09, 24 June 2011 (UTC)

History/Golgi[edit]

I just read about this information from Psychology of Behavior by Neil Carlson (2013), and I like the way the book went into a small history about Golgi cells. Camillo Golgi assumed that astrocytes were responsible for providing nutrient to the neurons from the capillaries, then disposing of the waste products (some of this is mentioned in this article). A suggestion I have is to mention this idea that was not accepted right away and describing how glucose it taken from the capillaries by astrocytes. Cbruha11 (talk) 04:58, 27 February 2014 (UTC)