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Wikipedia CD Selection
WikiProject icon Avocado is included in the Wikipedia CD Selection, see Avocado at Schools Wikipedia. Please maintain high quality standards; if you are an established editor your last version in the article history may be used so please don't leave the article with unresolved issues, and make an extra effort to include free images, because non-free images cannot be used on the DVDs.

"A" and "B cultivars" are confusing; could explain what a cultivar is and what each subheading means more. Could add a header to put subheadings "A" and "B cultivars" under instead of just having them under "Cultivation in Peru". Mosenga17 (talk) 03:01, 21 October 2016 (UTC)

Under "Culinary Uses" the pictures added could use citations of where the pictures came from. If they came from a restaurant website you should site which restaurant it came from and what the dish is called. Mosenga17 (talk) 03:08, 21 October 2016 (UTC)

Medicinal Applications of Avocado Lipids[edit]

Avocatin B, a lipid derived from the avocado pit, has been studied for its use in anticancer therapy, particularly in the treatment of Acute Myeloid Leukemia (AML).[1] The 17 carbon fatty acid has been found to selectively localize in the mitochondrias of cancerous hematopoetic stem cells which results in an inhibition of fatty acid oxidation. The lipotoxicity resulting from the accumulation of reactive oxygen species which can induce apoptosis and lead to a reduction of AML cells in the body.

Enzymatic Browning of Avocados[edit]

Oxidation of catechol and subsequent polymerization

When the avocado flesh is exposed to oxygen, phenols, such as catechol, distributed ubiquitously throughout the flesh are able to undergo oxidation catalyzed by the enzyme Catechol Oxidase. This enzyme contains an active site composed of two copper (II) atoms, coordinated by histidine residues, which can bind an oxidizing agent, such as oxygen, and use it to reduce the phenol substituents on catechol. The resulting species, 1,2-benzoquinone, can then undergo non-enzymatic oxidative condensation with amino acids, proteins, phenols, or other quinones to form complex brown polymers called Melanins which produce the phenotype in question.

  1. ^ "Targeting Mitochondria with Avocatin B Induces Selective Leukemia Cell Death". Cancer Research. 75 (12). June 15, 2015.