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I guess that this page should be fusionated with Carcinod Syndrome
This page is a bit of a stump. Can someone competent expand on it? Maybe a section about tumour markers and diagnostic? Mortality and impact on life quality? --Jan
There's 3 subjects which need merging/coordinating: carcinoid, carcinoid syndrome and neuroendocrine tumor. At the very least there should be easy links between the 3 Danielbirns (talk) 23:35, 5 February 2011 (UTC)
Larry Kvols MD of Moffitt Cancer Center and Research Institute in Tampa, in "Carcinoid Tumors and the Carcinoid Syndrome: What's New in the Therapeutic Pipeline", presented at the Carcinoid Cancer Foundation's Carcinoid Symposium 2002, stresses flushing, diarrhea, CHF, and asthma as the four critical characteristics of carcinoid syndrome.
TH 06:35, 27 July 2006 (UTC)
I suspect that the writer of this section may be mistaking the 5-10% incidence of carcinoid syndrome among carcinoid patients with a 5-10% incidence of secretion. I don't think that's true. Rather, the majority of carcinoids occur in regions drained by the mesenteric vasculature, leading to metabolism of serotonin to 5-HIAA in the liver before it reaches systemic circulation, preventing the evolution of carcinoid syndrome.
There's a list of markers, and a discussion of diagnosis, at neuroendocrine tumor.
TH 01:35, 29 July 2006 (UTC)
please check Neuroendocrine Tumor article
See the neuroendocrine tumors discussion page for statistical citations.
I invite all interested parties to edit or criticize neuroendocrine tumors. Citations are on its discussion page.
TH 02:17, 16 August 2006 (UTC)
Most common site of incidence of carcinoids is not the appendix!
As per the PAN-SEER data, the most common site for carcinoids is the foregut; bronchial carcinoids constituting the most common ones! Midgut is second in line with ileum constituting the second most prevalent site. And hindgut with rectum alone constitutes 13.6% cases. The appendix constitutes only 4.8% of all cases!
Serotonin Synthesis of Carcinoid
Serotonin is synthesized from the amino acid tryptophan. Tryptophan is also used to synthesize niacin. In carcinoid, a larger percentage of the tryptophan is converted to serotonin. This can lead to a niacin deficiency leading to the development of pellagrous symptoms. —Preceding unsigned comment added by 220.127.116.11 (talk) 02:12, 28 February 2008 (UTC)
My corrections would be. Interferon is sometimes helpful, not a regular treatment 2015. The article states 6% incidence of Carcinoid Syndrome. This happens usually when the cancer has spread to the liver or elsewhere, usually. Think the incidence is much higher than 6% All Carcinoids "have malignant potential", I think it is correct to say all carcinoids are malignant. 18.104.22.168 (talk) 04:07, 27 July 2015 (UTC) 22.214.171.124 (talk) 04:10, 27 July 2015 (UTC)