Talk:Cell membrane

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edit·history·watch·refresh Stock post message.svg To-do list for Cell membrane:


a cell wall is a biological membrane that helps the cell seperate all the interior of a cells. come on people gosh just stupid I mean like what the heck.

Not written by the above writer. If the cell membrane (plasma membrane) "is a biological membrane that separates the interior of all cells from the outside environment," then does such a definition make it seem that the cell wall of a cell is in the "outside environment"? Perhaps the definition should be concerned with the cytoplasm--for example, "the plasma membrane surrounds the cytoplasm."

Also, if the cell in the associated diagram contains cholesterol, then must it not be some type of animal cell? And if it is an animal cell, then should the diagram be entitled "Animal-cell membrane" rather than "Cell membrane"? And should "Illustration of a Eukaryotic cell membrane" read instead "Illustration of a Eukaryotic animal-cell membrane"? — Preceding unsigned comment added by Yurugu (talkcontribs) 12:58, 23 June 2014 (UTC)


Can someone well-versed on this topic incorporate Caveolae into this article? Kingturtle 00:08 May 14, 2003 (UTC)

No I can't help you out, Kingturtle...I'm sorry. If you are a teacher, I strongly recommend this site to your students. I am a high schooler in biology and have found this site very helpful in looking up words and information. Plus, it's free!! I strongly recommend it! Happy exploring with Wikipedia!!!!

I think it's worth having a separate article; research in the field is ongoing and the caveolae article could potentially expand considerably. It should be linked from here, though; it it? I'll check. --Chinasaur 00:39, 8 Sep 2004 (UTC)

ERE —Preceding unsigned comment added by (talk) 03:42, 25 November 2009 (UTC)


I can't do it right now, but someone should add a section to this article about: 1) junctions between the cell membrane (i.e. desmosomes, tight junctions, hemidesmosomes, etc.) 2) all three transports (right now there are only two - all three are simple, facilitated, and active).

I also can't do it right now, but someone should add a section on apical and basolateral membrane, and redirects too. --Eleassar777 14:34, 24 May 2005 (UTC)

Artificial outer membranes[edit]

I added today an article about polymersomes and checked out the liposome article. Both are currently stubs. I don't have the expertise required to write about them beyond what I already wrote (and that's not much and probably lacking in various aspects) but it would be nice if someone qualified could write them.

Link to this article should be added as well, as should links to them be added to this article. I'd also be very pleased if someone could start an article about artificial cells. --Khokkanen 10:34, 12 July 2005 (UTC)

Structure of biological membranes[edit]

This needs to be improved. I inserted a few phrases, please fell free to edit anything. Note that biological membranes include carbohydrate component, in addition to lipids and proteins. Biophys 02:45, 30 January 2007 (UTC) I HATE IT — Preceding unsigned comment added by (talk) 21:38, 1 March 2013 (UTC)

Fluid mosaic model[edit]

Fluid mosaic model redirects here. I think it might be better to add that topic to biological membrane though, for the simple reasion that it is more general while this article is the more specific case. A cell has other membranes besides its plasma membrane, but the lipid bilayer/fluid mosaic model applies to all of them. - tameeria 04:24, 9 March 2007 (UTC)

I would like to make a small article describing the fluid mosaic model, and will be working on this over the next week. This article already exists in other languages. - charnixon 14:25, 28 November 2014 (PT)

Illustration of a cell membrane[edit]

This picture is not correct. The legend of this figure sounds weird to me. I've got the impression it mixes different systems of protein classification: the integral protein is globular, the transmembrane helix is intergral, the channel protein is a transport protein, peripheral protein are different from surface protein... that's very confusing! The term "globular" is rarely, if not never, used for membrane proteins. It qualifies the shape of (soluble) proteins. Actually, this is the opposite of "fibrous proteins". The integral proteins, as shown on the picture, are bi/polytopic proteins in fact. Integral means "tighly bound to the membrane", and not necessarly transmembrane. In the same idea, "peripheral" means "not tighly bound to the membrane". Only biochemical tests can say if the case for a specific protein... So the "peripheral" protein showm in the picture is in fact a monotopic protein. That's all you can say without performing tests. Actually, the surface protein is probably also a peripheral proteins. Finally, cholesterols look oriented in the wrong sense with their aliphatic tails oreitned toward the hydrophilic heads of phospholipids. cheers. -- 22:56, 23 April 2007 (UTC)

also, "peripheral" is spelt wrong Crana 11:10, 7 May 2007 (UTC)

Protein functions in cell membranes[edit]

I'm proposing to merge the contents of the article Protein Function in Cell Membranes either into this one or into membrane protein. - tameeria (talk) 02:22, 9 December 2007 (UTC)

I'm behind you on that. I think that membrane protein would be the more appropriate place to merge it. – ClockworkSoul 05:13, 19 April 2008 (UTC)
I just did it, there was very little in "Protein Function" to salvage.Biophys (talk) 00:43, 20 April 2009 (UTC)

Cell Membrane Difference[edit]

In the article, it says there are different type of cell membrane in different cells. In effect, does it mean a plant cell's membrane have the different composition than an animal's cell's membrane? And should we state it?Rider555 (talk) 02:25, 19 April 2008 (UTC) Rider555

New diagram of cell membrane[edit]

I did significant work on the cell membrane image when it was a Featured Picture Candidate and thought that the article could benefit from it. It shows the membrane more clearly and places it in context within the cell. Also shown are a more detailed view of the bilayer and phospholipids that make up a critical part of the membrane. If you have any corrections or suggestions I would like to hear them. Dhatfield (talk) 15:43, 18 June 2008 (UTC)

A non-technical alternative?[edit]

This page is a very in depth view of the cell membrane, scientifically precise etc. But it's hugely daunting to someone without a deep biological background. There's no link to an alternative laymans version of the page, and simple english wikipedia's version[1] has barely any content. Any chance of some of you working on either a laymans wiki page under a slight variant name (I'm not sure how standard they are, but maths articles often do so) or working on the Simple English version? - (talk) 16:19, 28 March 2009 (UTC)

Agreed. This is a subject I do understand, but I still think it should be more accessible. There's no point in having an article if the only people who can understand it are the people who already know the topic. —Preceding unsigned comment added by (talk) 17:14, 6 April 2009 (UTC)

Membrane Cholesterol[edit]

The high molecular percentage of cholesterol required by membranes (20% molecular) and lipid rafts (up to 50% molecular)makes its absence from lipid membrane text and diagrams one of the huge enigmas of modern cell membrane science. Most trans-membrane functions will seriously slow down if cholesterol is reduced by 9%.
example: Author: Waseem, Tatyana V;Kolos, Viktoriya A;Lapatsina, Liudmila P;Fedorovich, Sergei V Title: Influence of cholesterol depletion in plasma membrane of rat brain synaptosomes on calcium-dependent and calcium-independent exocytosis Journal: Neurosci Lett Volume: 405 Year: 2006 Pages: 106-10
Glynwiki (talk) 16:49, 30 May 2009 (UTC)


I've never heard the term "mandoflorpes", let alone in conjunction with the plasma membrane. A Google search for the term yields no results apart from this page and pages that have obviously copied this page word-for-word. Is this a typo, perhaps? M0rg4n (talk) 03:56, 3 March 2010 (UTC)

Just gibberish added by an IP editor. Removed. Tim Vickers (talk) 23:10, 3 March 2010 (UTC)

sizes of elements are missing[edit]

Sizes of the various membrane elements are missing. Please add. —Preceding unsigned comment added by (talk) 15:04, 13 March 2010 (UTC)

Edit request from, 24 January 2011[edit]

{{edit semi-protected}} under the section "in simpler terms" talking about the lipid bilayer, it is written that the tails are hydrophilic and the heads are hydrophobic. this is the opposite of the truth and should be changed. it is even written elsewhere on the article that the tails are hydrophobic and the heads are hydrophilic (talk) 02:36, 24 January 2011 (UTC)

Done Stickee (talk) 06:02, 24 January 2011 (UTC)

cell membrane - plasma membrane - Synonyms?[edit]

Plasma membrane is a redirect to this article, and is used later in it - but there isnt any definition - synonyms? Christian75 20:11, 17 July 2011 (UTC)

This article is somewhat confusing - cell membranes actually include internal membranes. Plasma membrane is the outer membrane and is generally different (contains glycolipids and glycoproteins on the outer side) than many of the inner membranes. This should be clarified. — Preceding unsigned comment added by Membrane-biologist (talkcontribs) 02:51, 26 August 2012 (UTC)

a cytoplasm is the gel like material that surrounds the internal parts of the cell!!! knowledge speaks to me and don't ask what im talking about but if you know you are smart if you didn't know you are stupid — Preceding unsigned comment added by (talk) 23:50, 2 October 2013 (UTC)

Semi-protected edit request on 5 December 2014[edit]

Please change

Fluid mosaic model[edit]

According to the fluid mosaic model of


Fluid mosaic model[edit]

According to the fluid mosaic model of

as I created a page describing the fluid mosaic model.

Charnixon (talk) 04:50, 5 December 2014 (UTC)

Yes check.svg Done - Arjayay (talk) 09:45, 5 December 2014 (UTC)

Semi-protected edit request on 23 March 2016[edit] (talk) 16:56, 23 March 2016 (UTC) the logs are not updated and can get lots of changes in the new time

Not done; request incomprehensible. Pinkbeast (talk) 17:20, 23 March 2016 (UTC)

Assessment comment[edit]

The comment(s) below were originally left at Talk:Cell membrane/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.

Fluid mosaic model should get the top importance rating; it currently redirects here, which is not completely correct as it applies to biological membranes and not just the plasmalemma - tameeria 17:13, 18 February 2007 (UTC)

Last edited at 18:46, 21 October 2009 (UTC). Substituted at 11:07, 29 April 2016 (UTC)