Talk:Citric acid cycle

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Regulation Citations[edit]

I think it may be helpful to add a citation earlier on in first paragraph of the regulation section. In particular, the first few sentence discussing inhibition seem to have fairly strong wording, so I think a citation is warranted. The information seems to be correct, but I think it would help to know where it is from.Gruskyd (talk) 21:44, 14 March 2017 (UTC)

Citric Acid Cycle Diagram[edit]

This diagram is really messy. The molecules could be less bulky looking. (having the molecules not be the stick and ball structure and instead have it be the normal structural formula) Also having backwards arrows on some reactions would help identify which steps are reversible or not.

Geowong (talk) 18:25, 18 March 2017 (UTC)

Enzyme Filling Out/Clarification[edit]

This article is very light on mentioning the enzymatic mechanisms which drive the chemistry along, while the enzymes themselves do have separate pages their existance in this system overview has been sequestered to very few sections. –One edit that I think would be helpful would be to invoke the pyruvate dehydrogenase complex in more than just the Regulation section. More specifically to use it in sections 1,3,9 of the article at minimum to better describe how the CAC fits in with other metabolic pathways, as well as describing one important pathway of acetyl CoA formation. If we go that far it might also be helpful to link in the other processes that can produce Acetyl-CoA, or oxaloacetate which can be incorporated into the cycle as they diffuse into the mitochondria. - A second enzymatic suggestion would be to link the enzymes to the type of reaction (dehydrogenation, hydration, etc) that is effected by the enzyme as a part of that step. 22:09, 20 March 2017 (UTC) 22:10, 20 March 2017 (UTC)Maasher (talk)